Manchester United vs Arsenal: Predicted XI for Red Devils As Amorim Makes Tough Decision on Sesko
- Andre Onana is set to return in goal for Manchester United despite missing pre-season through injury
- Summer signing Benjamin Sesko is also tipped for his Premier League debut against Arsenal as the club’s chosen striker
- Amorim is set to deploy his three new signings in attack as Man United aim to end Arsenal’s winning streak
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Manchester United open their 2025/26 Premier League campaign with a blockbuster clash against Arsenal at Old Trafford on Sunday.
Manager Ruben Amorim faces a high-stakes start, with several key selection decisions to make in his first competitive match in charge this season against the Gunners.

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The Red Devils had their worst finish in the Premier League last season, and Amorim would be eager to have a perfect start to their 2025/26 campaign after making investments in his squad.
Bryan Mbeumo, Matheus Cunha, and Benjamin Sesko are three major forwards that Manchester United has signed this summer, and fans are confident that these players can change their fortunes against Arsenal on the opening weekend.
Man United have not won the title since Ferguson left in 2013, whilst the situation is even worse for Arsenal.
As documented by Give Me Sport, the Gunners are on a 21-year Premier League title drought, and have finished as runners-up for the past three consecutive seasons.
Arsenal are currently on an impressive streak of four consecutive victories over United in the Premier League.
Predicted starting XI for Man United vs Arsenal
Goalkeeper – Andre Onana
According to Daily Express, Andre Onana is expected to return between the posts despite missing the entirety of pre-season with a hamstring injury.
His experience and ability to build play from the back will be crucial against Mikel Arteta’s pressing Arsenal side.
Defenders - Leny Yoro, Matthijs de Ligt, Luke Shaw
In defence, Leny Yoro, Matthijs de Ligt, and Luke Shaw are tipped to form the back three.
Yoro has impressed with his physical development over the summer, while De Ligt appears to have edged Harry Maguire for a starting spot.
Shaw will provide balance on the left, with Lisandro Martinez still recovering from a knee injury sustained in February.
Midfielders - Amad, Casemiro, Fernandes, Dorgu
Amad is in line to start as the right-wing-back, having impressed in pre-season with his attacking flair.
On the opposite flank, 20-year-old Patrick Dorgu will look to make an early statement, bringing pace and width from the left after the departure of some key players in defence.

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Casemiro is expected to anchor the midfield alongside Bruno Fernandes. While the Brazilian’s legs have been questioned, his leadership remains invaluable.
Fernandes will carry the creative burden, looking to feed United’s new-look attack. Amorim has hinted at the need for more athleticism in midfield, but for now, this pairing looks set to start.
Attackers - Mbeumo, Cunha, Sesko
Benjamin Sesko is likely to make his Premier League debut with Rasmus Hojlund out of Amorim’s plans and Joshua Zirkzee lacking match sharpness.
Supporting him will be summer signings Bryan Mbeumo and Matheus Cunha in dual No. 10 roles.
This trio represents the heart of Amorim’s attacking overhaul, with all three expected to bring directness that Manchester United lacked last season.
6 players to miss Man United vs Arsenal
Earlier, Legit.ng reported that ahead of the Premier League opener, both Man United and Arsenal face significant injury concerns, with up to six key players likely to miss the big game.
Andre Onana is facing a tight deadline to recover from a troublesome hamstring injury that ruled him out of the entire pre-season.
Source: Legit.ng